Finally finished Sweet Tooth.  There's another beginning & ending comparison where the Cessna 152 spotted in episode 1 is sitting crashed in a field, 10 years later.  Of course, everyone manages to get captured either by bungling or on purpose.

There was no resolution, just the setup for season 2.  The show never figured out why the bad guys were out to exterminate the hybrids because they were the "immigrants" if they simultaneously needed the hybrids for the cure.  Then they needed to kill the hybrids to harvest their thyroid hormones & study them, but not until after they reached a certain age & were captured alive.

The war between the humans & hybrids was a bit contrived.  There's the evil general who also happens to be the only one looking for a cure.  There's a start of an anti vaxxer storyline where finding a cure isn't righteous & the humans are supposed to go extinct, but simultaneously the incompetent doctor wants to save his wife & incompetent tooth wants to find his mom alive, who are both the humans whose existence isn't righteous.